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Table 4 Univariate predictors of recurrence-free survival in patients initially treated with local treatment

From: Upfront surgery is not advantageous compared to more conservative treatments such as observation or medical treatment for patients with desmoid tumors

Variable Patients (n) 5-year recurrence-free survival (95% CI, %) P value
Age at diagnosis (years)
 ≤30 22 72.4 (50.6–87.1) 0.711
 > 30 38 62.8 (44.6–78.0)
Sex
 Male 23 50.2 (30.1–70.2) 0.021a
 Female 37 76.9 (58.4–88.8)
Tumor site
 Extremities 30 70.2 (50.4–84.6) 0.571
 Non-extremities 30 63.0 (43.3–79.2)
Tumor size (cm)
 ≤5 17 86.9 (59.6–96.7) 0.295
 5<, < 10 25 62.1 (41.5–79.1)
 ≥10 18 55.2 (29.2–78.6)
Previous surgery or trauma at the site of the primary tumor
 Yes 9 77.8 (42.1–94.4) 0.936
 No 51 65.0 (49.9–91.7)
Year of diagnosis
 1999–2009 48 65.1 (49.5–78.0) 0.750
 2010–2018 12 75.0 (44.8–91.7)  
Biopsy
 Core needle biopsy 38 70.4 (52.8–83.5) 0.251
 Open biopsy 22 60.6 (38.2–79.2)
Adjuvant radiotherapy
 No 45 73.0 (57.2–84.5) 0.110
 Yes 15 48.6 (23.8–74.1)  
Surgical margin
 R0 29 67.7 (48.4–82.4) 0.976
 R1/2 31 66.4 (46.5–81.8)  
  1. aStatistically significant. Macroscopic incomplete resection, R2; microscopic incomplete resection, R1; microscopic complete resection, R0
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