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Table 3 Univariate predictors of event-free survival

From: Upfront surgery is not advantageous compared to more conservative treatments such as observation or medical treatment for patients with desmoid tumors

Variable Patients (n) 5-year event-free survival (95% CI, %) P value
Age at diagnosis (years)
 ≤30 35 70.2 (52.8–83.3) 0.764
 > 30 64 69.8 (56.3–80.6)
Sex
 Male 37 56.3 (39.3–71.9) 0.024a
 Female 62 77.8 (64.4–87.1)
Tumor site
 Extremities 49 66.9 (51.8–79.1) 0.522
 Non-extremities 50 73.1 (58.0–84.3)
Tumor size (cm)
 ≤5 25 82.8 (61.8–93.5) 0.345
 5<, < 10 37 71.3 (54.2–83.9)
 ≥10 37 60.1 (41.9–75.9)
Previous surgery or trauma at the site of the primary tumor
 Yes 14 77.1 (47.9–92.5) 0.998
 No 85 68.8 (57.4–78.3)
Year of diagnosis
 1999–2009 61 64.9 (51.1–76.6) 0.372
 2010–2018 38 78.8 (63.0–89.0)  
Biopsy
 Core needle biopsy 70 72.9 (60.4–82.6) 0.190
 Open biopsy 29 63.2 (43.7–79.2)
Initial treatment
 Local treatment 60 66.8 (53.0–78.2) 0.509
 Observation/medical treatment 39 75.2 (58.6–86.7)
  1. aStatistically significant
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