Fig. 1

MRI of the brain, lower limb muscles and spinal cord. a Cerebral MRI showed abnormal signals in the subcortical white matter near the horns of the right lateral ventricle, which is high in T2-weighted imaging (black arrows), low in T1-weighted imaging and high in fluid attenuated inversion recovery (not shown). b The pelvic girdle and thigh muscles demonstrated obvious atrophy and fat infiltration of pectineus (a), vastus lateralis (b), iliopsoas (c), obturator externus (d) and gluteus maximus (e) (white arrows), while the sartorius (f), rectus femoris (g, i), tensor fascia lata (h), adductor longus (j) and gracilis (k) (white hollow arrows) were intact. Image of the legs revealed a moderate fat infiltration of the tibialis posterior (white hollow triangle). c The spinal cord did not exhibit atrophy