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Table 4 Between-group changes in pressure pain threshold for responder vs non-responders following SMT

From: Changes in pain sensitivity and spinal stiffness in relation to responder status following spinal manipulative therapy in chronic low Back pain: a secondary explorative analysis of a randomized trial

Time Improvement ODI NRS
Pain Stiff Pain Stiff
Baseline 50% 96(−70:262) −42(− 232:148) 75(− 124:275) 13(− 195:222)
30% 56(− 96:209) −71(− 232:91) 33(− 136:203) 17(− 143:176)
0% −37(− 226:152) − 84(− 275:108) − 39(− 217:140) −75(− 255:105)
Post-SMT 50% 15(− 92:122) 74(− 56:204) 96(− 32:225) 79(− 57:215)
30% 6(−92:105) 115 (10:220)* 69(−41:180) 11(−98:119)
0% −43(− 172:86) 108(−4:219) 61(−54:176) 32(− 86:150)
Follow-up 50% 73(−39:184) 54(−73:181) 147 (14:281)* 51(−86:187)
30% 26(−74:126) 119 (12:226)* 121 (5:237)* 8(− 101:117)
0% −16(−142:110) 98(−17:213) 59(−60:177) 74(−43:191)
  1. Between-group mean differences (responder vs non-responder) in pressure pain threshold (kPa) at varying thresholds for improvement in disability and patient-reported low back pain (0, 30, 50%) in groups randomized to SMT at the stiffest (‘stiff’) or most pain sensitive (‘pain’) segment (columns). Estimates are presented as between-group differences, 95% confidence interval, and “*” indicates a p-value < 0.05. ODI Oswestry disability index, NRS patient-reported low back pain