Fig. 4
From: LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis
Identification of FRK as a target gene of miR-663a. a Schematic diagram of predicted binding sites of miR-663a in FRK. b Determination of luciferase activity in the OA chondrocytes. c The mRNA and protein expression of FRK in OA chondrocytes. d The effects of miR-663a on the the protein expression of FRK in OA chondrocytes. e The effects of HOTTIP on the the protein expression of FRK in OA chondrocytes. f The protein expression of FRK in OA cartilage tissues. g Determination of the expression of FRK in human OA cartilage (n = 30) and normal cartilage (n = 30) by qRT-PCR. h The correlation analysis of miR-663a and FRK gene expression in OA cartilage tissue. *P < 0.05