Skip to main content
Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis

Fig. 2

Identification of miR-663a as a target gene of lncRNA-HOTTIP. a Schematic diagram of predicted HOTTIP binding sites in miR-663a. b Determination of the expression of miR-663a in OA chondrocytes transfected with si-HOTTIP or pcDNA-HOTTIP. c Determination of luciferase activity in the OA chondrocyte model. d Determination of the relative enrichment of miR-663a in the OA chondrocyte model transfected with HOTTIP-Bio by RNA pull-down. e Determination of the expression of miR-663a in human OA cartilage (n = 30) and normal cartilage (n = 30) by qRT-PCR. f The correlation analysis of HOTTIP and miR-663a gene expression in OA cartilage tissue. * P < 0.05

Back to article page