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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: LncRNA HOTTIP leads to osteoarthritis progression via regulating miR-663a/ Fyn-related kinase axis

Fig. 1

Effects of HOTTIP on proliferation and apoptosis of IL-1β-induced chondrocytes. a Determination of the expression of HOTTIP in human OA cartilage (n = 30) and normal cartilage (n = 30) by qRT-PCR. b Determination of the expression of HOTTIP in OA chondrocytes transfected with si-HOTTIP or pcDNA-HOTTIP. c, d Determination of the proliferation activity of OA chondrocytes transfected with pcDNA-HOTTIP (c) or si-HOTTIP (D) by CCK-8. e, f Determination of the colony formation ability of OA chondrocytes transfected with pcDNA-HOTTIP (e) or si-HOTTIP (f) by colony formation. g, h Determination of the percentage of apoptosis in OA chondrocytes transfected with pcDNA-HOTTIP (g) orsi-HOTTIP (h) by flow cytometry. *P < 0.05

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