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Table 3 Incidence of herpes zoster by age, sex and comorbidity and Cox model measured hazards ratio for patients with Sciatica compared those without Sciatica

From: Herpes zoster in patients with sciatica

Variables Sciatica Crude HR (95% CI) Adjusted HRb (95% CI)
No Yes
Event PY Ratea Event PY Ratea
Age, years
  ≤ 49 662 154,980 4.27 889 155,671 5.71 1.34 (1.21, 1.48)*** 1.17 (1.04, 1.31)***
 50–64 1174 127,099 9.24 1665 127,623 13.1 1.41 (1.31, 1.52)*** 1.30 (1.19, 1.41)***
 65+ 1063 86,700 12.3 1427 92,682 15.4 1.25 (1.16, 1.36)*** 1.11 (1.02, 1.21)***
Sex
 Female 1758 211,353 8.32 2434 214,784 11.3 1.36 (1.28, 1.45)*** 1.21 (1.14, 1.30)***
 Male 1141 157,426 7.25 1547 161,192 9.60 1.32 (1.23, 1.43)*** 1.14 (1.04, 1.24)***
Comorbidity c
 No 1242 213,614 5.81 586 73,197 8.01 1.35 (1.22, 1.49)*** 1.37 (1.24, 1.51)***
 Yes 1657 155,164 10.7 3395 302,780 11.2 1.04 (0.98, 1.11) 1.14 (1.08, 1.21)***
  1. Ratea, incidence rate, per 1000 person-years; Crude HR, relative hazard ratio; Adjusted HRb: multivariable analysis including age, sex, and comorbidities of diabetes, CAD, and lumbar disc herniation;
  2. cIndividuals with any comorbidity of diabetes, CAD, depression, and chronic kidney disease, obesity, cancer, and lumbar disc herniation were classified into the comorbidity group
  3. ***p < 0.001