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Table 2 The incidence and risk factors for herpes zoster

From: Herpes zoster in patients with sciatica

Variable Event PY Ratea Crude HR(95% CI) Adjusted HRb
(95% CI)
Sciatica
 No 2899 368,778 7.86 1.00 1.00
 Yes 3981 375,977 10.6 1.35 (1.28, 1.41)*** 1.19 (1.12, 1.25)***
Age, year
  ≤ 49 1551 310,651 4.99 1.00 1.00
 50–64 2839 254,722 11.2 2.25 (2.11, 2.39)*** 2.10 (1.97, 2.23)***
 65+ 2490 179,382 13.9 2.84 (2.67, 3.03)*** 2.48 (2.32, 2.66)***
Sex
 Female 4192 426,137 9.84 1.16 (1.11, 1.22)*** 1.07 (1.02, 1.12)*
 Male 2688 318,618 8.44 1.00 1.00
Comorbidity
 Diabetes
  No 6113 690,290 8.86 1.00 1.00
  Yes 767 54,465 14.1 1.61 (1.50, 1.74)*** 1.14 (1.05, 1.12)**
 CAD
  No 5039 615,072 8.19 1.00 1.00
  Yes 1841 129,683 14.2 1.75 (1.66, 1.85)*** 1.18 (1.12, 1.25)***
 Depression
  No 6455 709,775 9.09 1.00 1.00
  Yes 425 34,980 12.2 1.36 (1.23, 1.50)*** 1.11 (1.01, 1.23)*
 Chronic kidney disease
  No 6727 735,561 9.15 1.00 1.00
  Yes 153 9193 16.6 1.88 (1.60, 2.20)*** 1.28 (1.09, 1.50)**
 Obesity
  No 6788 735,209 9.23 1.00 1.00
  Yes 92 9546 9.64 1.06 (0.87, 1.31)  
 Cancer
  No 6691 730,816 9.16 1.00 1.00
  Yes 189 13,939 13.6 1.51 (1.31, 1.75)*** 1.21 (1.05, 1.40)*
 Lumbar disc herniation
  No 2538 348,796 7.28 1.00 1.00
  Yes 4342 395,959 11.0 1.53 (1.46, 1.61)*** 1.24 (1.17, 1.31)***
  1. Ratea, incidence rate, per 1000 person-years; Crude HR, relative hazard ratio; Adjusted HRb: multivariable analysis including age, sex, and comorbidities of diabetes, and CAD;
  2. *p < 0.05, **p < 0.01, ***p < 0.001