From: Bone phenotypes in rheumatology – there is more to bone than just bone
Biomarker | Disease Levels compared to healthy | Findings | References |
---|---|---|---|
Bone turnover | |||
CTX-I | Conflicting reports | – | |
ICTP | Conflicting reports | – | |
Osteocalcin | Increased, but conflicting reports | – | |
C1M | Increased | – | [186] |
BALP | Increased, but conflicting reports | – | |
Cartilage Turnover | |||
CTX-II | Increased | – | [189] |
C2M | No difference | – | [190] |
C2C | Increased | – | [191] |
PIIANP | Increased | – | [192] |
PIIBNP | Increased | – | [193] |
CPII | Increased | – | [191] |
COMP | Increased in synovial fluid compared to RA | No clear correlation with disease activity |