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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Joint hemorrhage accelerates cartilage degeneration in a rat immobilized knee model

Fig. 2

Time-lapse changes in the femoral and tibial cartilage in the contact area. Mankin score of the Im-B group was significantly higher than that of the Im-NS group at 4 weeks in the femurs and 4 and 8 weeks in the tibias (a and d). The number of chondrocytes in the Im-B group significantly decreased at 3 days and 8 weeks in the femur and 3 days and 1 and 8 weeks in the tibia compared with that in the Im-NS group (b and e). Cartilage thickness did not change and was not affected by immobilization and intra-articular administration (c and f, Fig. 3c and f)

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