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Table 1 The differential diagnosis using triphasic bone scan

From: Diagnosis and treatment of intramedullary osteosclerosis: a report of three cases and literature review

Phase

Malignancy [13]

Osteomyelitis [13]

Stress fracture [14]

IMOS [1], [our cases]

Phase 1: Vascular phase

Enhanced blood flow

Enhanced blood flow

Relatively poor sensitivity

Absent

Phase 2: Soft tissue (Blood pool)

Soft-tissue hyperemia

Soft-tissue hyperemia

Lateral/medial blood pool imaging was positive and significantly better than anterior/posterior images

Absent or slightly uptake

Phase 3: Delayed (bone)

Increased uptake

Increased uptake

Focal increased tracer uptake

Fusiform-shaped intense area of the tracer uptake