Fig. 1
From: Proteasome inhibitors reduce thrombospondin-1 release in human dysferlin-deficient myotubes
Effect of Vitamin D3 and EB1089 on healthy control myotubes. a Quantification of WB bands of untreated wild-type myotubes (C- ), Vitamin D3 and EB1089 treated wild-type myotubes for 24 h. Vitamin D3 treatment produced an increase in dysferlin expression compared to non-treated myotubes. However, only EB1089 showed a significant increase compared to non-treated myotubes. b Representative WB of dysferlin with vitamin D3 and EB1089 treatment. Desmin was used as a loading control. Data are represented as mean of 3 replicates ± standard deviation. Fold-change is calculated over the results of dysferlin expression in non-treated WT myotubes. Results were statistically analyzed using one-way Anova followed by Tukey post hoc test. Statistical significance was set at p < 0.05. *p < 0.05