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Table 2 Lab tests and culture results among patients with and without inflammatory diseases at spacer insertion

From: Two-stage exchange Arthroplasty is a viable treatment for Periprosthetic joint infection in inflammatory diseases

  Non-inflammatory diseases(n = 159) Inflammatory diseases(n = 25) P-value
Serum biomarkers, mean (SD)
 CRP (mg/l) 29.9 (33.4) 23.3 (22.4) 0.552
 IL-6 (pg/ml) 30.03 (97.49) 22.54 (34.22) 0.991
 ESR, (mm/h) 44.34 (26.76) 38.27 (22.14) 0.370
 Fibrinogen, (g/l) 5.05 (1.30) 4.83 (1.12) 0.164
 D-dimer, (g/ml) 1.92 (1.44) 1.23 (0.64) 0.106
Mean Synovial WBC, 109/ml (SD) 23,994.78 (30,090.00) 20,571.67 (34,426.31) 0.406
Microbiology results, n (%)
Staphylococcus aureus 33 (20.75) 3 (12.00) 0.286
 Coagulase negative Staphylococcus 42 (26.42) 5 (20.00) 0.373
Enterococcus faecalis 9 (5.66) 1 (4.00) 1.000
 Streptococcus 5 (3.14) 1 (4.00) 0.577
 Gram negative bacillus 12 (7.55) 2 (8.00) 1.000
 Fungus 11 (6.92) 0 (0.00) 0.364
 Polymicrobial organisms 12 (7.55) 2 (8.00) 1.000
 Other organisms 5 (3.14) 0 (0.00) 1.000
Positive pathology *, n (%) 100 (62.77) 18 (73.68) 0.753
Sinus tract, n (%) 43 (27.22) 7 (28.00) 1.000
  1. ESR erythrocyte sedimentation rate, CRP c-reactive protein, IL-6 interleukin-6; positive pathology, more than 5 polymorphonuclear neutrophils (PMNs) per ×400 high-power field (HPF) in at least five HPFs