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Table 2 Lab tests and culture results among patients with and without inflammatory diseases at spacer insertion

From: Two-stage exchange Arthroplasty is a viable treatment for Periprosthetic joint infection in inflammatory diseases

 

Non-inflammatory diseases(n = 159)

Inflammatory diseases(n = 25)

P-value

Serum biomarkers, mean (SD)

 CRP (mg/l)

29.9 (33.4)

23.3 (22.4)

0.552

 IL-6 (pg/ml)

30.03 (97.49)

22.54 (34.22)

0.991

 ESR, (mm/h)

44.34 (26.76)

38.27 (22.14)

0.370

 Fibrinogen, (g/l)

5.05 (1.30)

4.83 (1.12)

0.164

 D-dimer, (g/ml)

1.92 (1.44)

1.23 (0.64)

0.106

Mean Synovial WBC, 109/ml (SD)

23,994.78 (30,090.00)

20,571.67 (34,426.31)

0.406

Microbiology results, n (%)

 Staphylococcus aureus

33 (20.75)

3 (12.00)

0.286

 Coagulase negative Staphylococcus

42 (26.42)

5 (20.00)

0.373

 Enterococcus faecalis

9 (5.66)

1 (4.00)

1.000

 Streptococcus

5 (3.14)

1 (4.00)

0.577

 Gram negative bacillus

12 (7.55)

2 (8.00)

1.000

 Fungus

11 (6.92)

0 (0.00)

0.364

 Polymicrobial organisms

12 (7.55)

2 (8.00)

1.000

 Other organisms

5 (3.14)

0 (0.00)

1.000

Positive pathology *, n (%)

100 (62.77)

18 (73.68)

0.753

Sinus tract, n (%)

43 (27.22)

7 (28.00)

1.000

  1. ESR erythrocyte sedimentation rate, CRP c-reactive protein, IL-6 interleukin-6; positive pathology, more than 5 polymorphonuclear neutrophils (PMNs) per ×400 high-power field (HPF) in at least five HPFs