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Table 5 Distribution of metals (median with 25th–75th percentiles) in tissues by Hart classification [24] of pseudotumours

From: Retention of metals in periprosthetic tissues of patients with metal-on-metal total hip arthroplasty is reflected in the synovial fluid to blood cobalt transfer ratio in the presence of a pseudotumour

 

No tumour (n 14)

Hart 1 (n 8)

Hart 2A (n 14)

Hart 2B (n 12)

Hart 3 (n 9)

Synovial fluid

(ppm)

(ppm)

(ppm)

(ppm)

(ppm)

Cr

7.69

2.24

0.85

4.12

1.88

(p = 0.308)

(0.51–37.02)

(0.23–17.11)

(0.29–4.22)

(0.78–36.56)

(0.22–27.62)

Co

1.91

0.62

0.38

2.11

1.18

(p = 0.202)

(0.35–14.23)

(0.07–4.38)

(0.21–2.33)

(0.24–4.66)

(0.40–3.39)

Mo

0.28

0.16

0.06

0.27

0.14

(p = 0.327)

(0.03–2.79)

(0.02–0.97)

(0.02–0.33)

(0.03–1.10)

(0.02–0.85)

Soft tissue

 Cr

115.00

410.00

45.00

370.00

260.00

(p = 0.463)

(15.00–1172.50)

(10.00–1077.50)

(0.00–120.00)

(0.00–1072.50)

(20.00–470.00)

 Co

26.85

53.50

3.80

10.40

19.40

(p = 0.197)

(2.55–157.40)

(2.10–85.48)

(0.35–12.80)

(0.50–53.88)

(11.40–47.50)

 Mo

3.05

11.75

1.10

2.10

5.70

(p = 0.328)

(0.50–30.85)

(0.38–23.55)

(0.10–2.33)

(0.10–13.93)

(0.90–9.80)

Whole blood

 Cr

0.022

0.008

0.004

0.015

0.003

(p = 0.142)

(0.002–0.029)

(0.001–0.027)

(0.002–0.009)

(0.003–0.030)

(0.002–0.022)

 Co

0.039

0.027

0.006

0.017

0.006

(p = 0.085)

(0.002–0.073)

(0.001–0.070)

(0.003–0.017)

(0.005–0.078)

(0.005–0.047)

  1. p-values from Kruskal-Wallis test