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Table 4 Cox model with time dependent covariates for subgroups of gender and age groups

From: A prospective study on cancer risk after total hip replacements for 41,402 patients linked to the Cancer registry of Norway

  # hips # cancer Total Before 10 years After 10 years Cox model with timedep covariates
SIR (95% CI) SIR (95% CI) SIR (95% CI) HR (95% CI) P
Men
  < 55 years
  Cemented 471 35 1.16 (0.78–1.55) 1.11 (0.63–1.58) 1.23 (0.59–1.88) 1 (reference)  
  Uncemented 896 68 0.98 (0.75–1.21) 1.00 (0.67–1.33) 0.94 (0.62–1.26) 0.91 (0.39–2.08) 0.82
  Hybrid 121 7 0.87 (0.23–1.52) 0.68 (0.01–1.35) 1.37 (0.00–2.92) 1.66 (0.32–8.63) 0.55
 55–64 years
  Cemented 2870 463 0.99 (0.90–1.08) 0.93 (0.82–1.03) 1.10 (0.93–1.26) 1 (reference)  
  Uncemented 1281 184 1.03 (0.88–1.18) 0.91 (0.74–1.08) 1.26 (0.97–1.54) 1.26 (0.89–1.79) 0.19
  Hybrid 287 52 1.05 (0.77–1.34) 1.03 (0.69–1.36) 1.09 (0.56–1.62) 0.94 (0.50–1.74) 0.83
 65–74 years
  Cemented 7082 1539 1.03 (0.98–1.08) 1.04 (0.98–1.10) 0.94 (0.84–1.04) 1 (reference)  
  Uncemented 571 91 1.12 (0.89–1.35) 1.09 (0.84–1.35) 1.18 (0.65–1.71) 1.14 (0.68–1.90) 0.63
  Hybrid 375 103 1.20 (0.97–1.43) 1.20 (0.93–1.46) 1.17 (0.71–1.63) 1.09 (0.69–1.72) 0.70
Women
  < 55 years
  Cemented 667 54 1.04 (0.77–1.32) 1.00 (0.67–1.34) 1.12 (0.63–1.61) 1 (reference)  
  Uncemented 1071 71 0.83 (0.63–1.02) 0.67 (0.45–0.89) 1.06 (0.72–1.41) 1.44 (0.70–2.98) 0.32
  Hybrid 148 11 1.03 (0.42–1.63) 0.98 (0.30–1.66) 1.18 (0.00–2.52) 1.07 (0.25–4.50) 0.93
 55–64 years
  Cemented 5610 656 1.04 (0.96–1.12) 1.00 (0.90–1.09) 1.12 (0.98–1.27) 1 (reference)  
  Uncemented 1938 234 1.27 (1.11–1.43) 1.24 (1.04–1.43) 1.33 (1.30–1.36) 0.94 (0.68–1.29) 0.69
  Hybrid 514 75 1,22 (0,95-1,50) 1,21 (0,89-1,54) 1,21 (0,71-1,72) 0.91 (0.54–1.54) 0.73
 65–74 years
  Cemented 15,834 2313 1.09 (1.04–1.13) 1.12 (1.06–1.17) 0.95 (0.88–1.03) 1 (reference)  
  Uncemented 922 95 1.08 (0.86–1.3) 1.12 (0.86–1.38) 0.93 (0.54–1.32) 0.90 (0.56–1.44) 0.65
  Hybrid 744 116 1.03 (0.84–1.21) 0.99 (0.77–1.21) 1.04 (0.72–1.36) 1.14 (0.78–1.68) 0.50