Table 3 SIR and Cox model with time dependent covariates for the excess risk after 10 years follow-up comparing different types of fixations
|  | #hips | #cancers | Total | Before 10 years | After 10 years | Cox model with time-dep. covariatesa | ||
|---|---|---|---|---|---|---|---|---|
SIR (95% CI) | SIR (95% CI) | SIR (95% CI) | HR b | (95% CI) | P | |||
Total: | 41,402 | 6167 | 1.06 (1.03–1.09) | 1.06 (1.03–1.09) | 1.02 (0.97–1.07) |  |  |  |
Cemented | 32,534 | 5060 | 1.05 (1.03–1.08) | 1.06 (1.03–1.09) | 0.99 (0.94–1.05) | 1 | (reference) | – |
Uncemented | 6679 | 743 | 1.08 (1.00–1.16) | 1.04 (0.94–1.13) | 1.16 (1.02–1.30) | 1.24 | (1.05–1.46) | 0.009 |
Hybrid | 2189 | 364 | 1.11 (0.99–1.22) | 1.09 (0.95–1.22) | 1.12 (0.91–1.33) | 1.07 | (0.85–1.35) | 0.55 |
< 55 years: | 3374 | 246 | 0.96 (0.84–1.08) | 0.89 (0.74–1.04) | 1.06 (0.86–1.26) |  |  |  |
Cemented | 1138 | 89 | 1.09 (0.86–1.31) | 1.04 (0.77–1.32) | 1.16 (0.77–1.56) | 1 | (reference) | – |
Uncemented | 1967 | 139 | 0.89 (0.75–1.04) | 0.80 (0.62–0.99) | 1.00 (0.76–1.24) | 1.19 | (0.69–2.05) | 0.54 |
Hybrid | 269 | 18 | 0.96 (0.52–1.40) | 0.85 (0.37–1.34) | 1.27 (0.25–2.29) | 1.31 | (0.45–3.82) | 0.62 |
55–64 years: | 12,500 | 1664 | 1.06 (1.01–1.11) | 1.00 (0.95–1.06) | 1.16 (1.06–1.25) |  |  |  |
Cemented | 8480 | 1119 | 1.02 (0.96–1.08) | 0.97 (0.90–1.04) | 1.11 (1.00–1.22) | 1 | (reference) | – |
Uncemented | 3219 | 418 | 1.15 (1.04–1.27) | 1.08 (0.95–1.21) | 1.29 (1.09–1.50) | 1.07 | (0.85–1.36) | 0.56 |
Hybrid | 801 | 127 | 1.15 (0.95–1.35) | 1.13 (0.90–1.36) | 1.16 (0.79–1.53) | 0.93 | (0.62–1.38) | 0.71 |
65–74 years: | 25,528 | 4257 | 1.07 (1.03–1.10) | 1.09 (1.05–1.12) | 0.96 (0.90–1.02) |  |  |  |
Cemented | 22,916 | 3852 | 1.06 (1.03–1.10) | 1.09 (1.05–1.13) | 0.95 (0.89–1.01) | 1 | (reference) | – |
Uncemented | 1493 | 186 | 1.10 (0.94–1.26) | 1.11 (0.93–1.29) | 1.03 (0.72–1.35) | 1.00 | (0.71–1.43) | 0.98 |
Hybrid | 1119 | 219 | 1.10 (0.96–1.25) | 1.09 (0.91–1.26) | 1.09 (0.82–1.35) | 1.12 | (0.83–1.51) | 0.46 |
Men: | 13,954 | 2542 | 1.03 (0.99–1.07) | 1.02 (0.97–1.07) | 1,03 (0.95–1.10) |  |  |  |
Cemented | 10,423 | 2037 | 1.02 (0.98–1.07) | 1.02 (0.97–1.07) | 0,99 (0.91–1.08) | 1 | (reference) | – |
Uncemented | 2748 | 343 | 1.04 (0.93–1.15) | 0.98 (0.85–1.11) | 1.15 (0.95–1.34) | 1.41 | (1.11–1.80) | 0.004 |
Hybrid | 783 | 162 | 1.13 (0.96–1.31) | 1.11 (0.91–1.31) | 1.15 (0.81–1.49) | 1.11 | (0.78–1.58) | 0.58 |
Women: | 27,448 | 3625 | 1.08 (1.05–1.12) | 1.09 (1.05–1.13) | 1.02 (0.96–1.08) |  |  |  |
Cemented | 22,111 | 3023 | 1.08 (1.04–1.12) | 1.09 (1.04–1.14) | 1.00 (0.93–1.06) | 1 | (reference) | – |
Uncemented | 3931 | 400 | 1.12 (1.01–1.23) | 1.09 (0.96–1.22) | 1.17 (0.97–1.36) | 1.09 | (0.87–1.36) | 0.47 |
Hybrid | 1406 | 202 | 1.09 (0.94–1.24) | 1.07 (0.89–1.24) | 1.10 (0.80–1.39) | 1.06 | (0.78–1.43) | 0.72 |