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Table 1 Serum levels of blood markers (pre-operative blood test) –elevated values are shown in red

From: Cherubism as a systemic skeletal disease: evidence from an aggressive case

Mineral metabolism and bone turnover markers

Serum marker

Normal range

Patient’s serum level

Calcium (mmol/L)

2.20–2.70 (all ages)

2.37

Phosphate (mmol/L)

1.3–1.85 (all ages)

2.10

PTH (ng/mL)

10–50 (all ages) [17]

54

CTx (pmol/L)

3875–14,260 (6 years) [18]

18,678

Osteocalcin (μg/L)

45.8–128 (6 years) [18]

121

PINP (ng/mL)

324–895.2 (6 years) [18]

1480

25OHD (ng/mL)

30–60 (all ages)

34

1.25(OH)2D (pg/mL)

45–102

(prepubertal children > 3 years) [19]

49

BALP (ng/mL)

39.6–98.9 (6 years) [18]

126.6

Inflammation exploration

Serum marker

Normal range

Patient’s serum level

CRP (mg/L)

<  6.0

2.9

IL-1 beta (pg/mL)

0–15

75.2

IL-6 (pg/mL)

0–8.6

4.1

IL-10 (pg/mL)

0–112

27.6

TNF alpha (pg/mL)

0–20

38.8

  1. PTH parathyroid hormone; CTx beta-C-terminal telopeptide; PINP procollagen type I N-terminal Propeptide; 25OHD 25-hydroxyvitamin D; 1.25(OH)2D 1,25-dihydroxyvitamin D; BALP bone isoenzyme alkaline phosphatase; CRP C Reactive Protein; IL Interleukin; TNF Tumor Necrosis Factor