Skip to main content

Table 1 Serum levels of blood markers (pre-operative blood test) –elevated values are shown in red

From: Cherubism as a systemic skeletal disease: evidence from an aggressive case

Mineral metabolism and bone turnover markers
Serum marker Normal range Patient’s serum level
Calcium (mmol/L) 2.20–2.70 (all ages) 2.37
Phosphate (mmol/L) 1.3–1.85 (all ages) 2.10
PTH (ng/mL) 10–50 (all ages) [17] 54
CTx (pmol/L) 3875–14,260 (6 years) [18] 18,678
Osteocalcin (μg/L) 45.8–128 (6 years) [18] 121
PINP (ng/mL) 324–895.2 (6 years) [18] 1480
25OHD (ng/mL) 30–60 (all ages) 34
1.25(OH)2D (pg/mL) 45–102
(prepubertal children > 3 years) [19]
49
BALP (ng/mL) 39.6–98.9 (6 years) [18] 126.6
Inflammation exploration
Serum marker Normal range Patient’s serum level
CRP (mg/L) <  6.0 2.9
IL-1 beta (pg/mL) 0–15 75.2
IL-6 (pg/mL) 0–8.6 4.1
IL-10 (pg/mL) 0–112 27.6
TNF alpha (pg/mL) 0–20 38.8
  1. PTH parathyroid hormone; CTx beta-C-terminal telopeptide; PINP procollagen type I N-terminal Propeptide; 25OHD 25-hydroxyvitamin D; 1.25(OH)2D 1,25-dihydroxyvitamin D; BALP bone isoenzyme alkaline phosphatase; CRP C Reactive Protein; IL Interleukin; TNF Tumor Necrosis Factor