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Table 2 Comparison of efficacy within the two groups based on changes from the baseline

From: Efficacy of single high-molecular-weight versus triple low-molecular-weight hyaluronic acid intra-articular injection among knee osteoarthritis patients

 

WOMAC

Lequesne

VAS

pain

stiffness

Function

Total

pain

walk

ADL

Total

VAS

HMW-HA [Mean]

 Before

9

3

30

42

5

2

5.5

12.5

8

 2 months

5

2

19

25

4

1

4.5

10

2

 6 months

5

1

17

22

3

1

4

8.5

3

 *P value

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

LMW-HA [Mean]

 Before

9

3

30

44

5.5

1

5.5

12.5

8

 2 months

5

1

18

25

3

1

4

9

2

 6 months

5

1

17

24.5

3.5

1

4.5

9.75

4

 *P value

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001

< 0.001#

< 0.001

  1. * P values refer to changes over time within each group, based on the Friedman test
  2. # P values refer to changes over time within each treatment group, based on Repeated Measures