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Table 5 Association between CARMEN variants and ONFH risk stratified by necrotic sites

From: Correlation analysis between CARMEN variants and alcohol-induced osteonecrosis of the femoral head in the Chinese population

SNP Model Genotype Frequency Without adjustment With adjustment
Case Control OR(95%CI) p-value OR(95%CI) p-value
rs12654195 codominant G/G 22 60 1   1  
   G/T 111 174 1.06 (0.76–1.48) 0.737 1.05 (0.75–1.47) 0.780
   T/T 109 181 0.61 (0.35–1.05) 0.073 0.61 (0.35–1.05) 0.074
  dominant G/G 22 60 1   1  
   G/T-T/T 220 355 0.94 (0.69–1.30) 0.722 0.94 (0.68–1.29) 0.688
  recessive G/G-G/T 133 234 1   1  
   T/T 109 181 0.59 (0.35–0.99) 0.046 0.60 (0.35–0.99) 0.049
  log-additive 142 174 0.86 (0.68–1.09) 0.219 0.86 (0.68–1.09) 0.211
  1. 95%CI 95% Confidence interval; OR Odds ratio; SNP Single-nucleotide polymorphism
  2. p-value: Calculated by Pearson χ2 test
  3. Bold type indicates statistical significance (p < 0.05)