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Table 2 Other characteristics of the included studies

From: The incidence of regression after the non-surgical treatment of symptomatic lumbar disc herniation: a systematic review and meta-analysis

Author Year Age Duration of symptom Nerve symptom Regression defined Follow-up
El Barzouhi et al. [9] 2013 18–65 6–12 W Yes Yes 1Y
Santilli et al. [10] 2006 18–65 Less than 10 D Yes Yes 45D
Fan et al. [11] 2015 Unknown Unknown Yes No 20D
Ahn et al. [12] 2002 19–73 (42.7) 1-10 W(median 4.5 W) Some Yes 3-11 M(11.9 M)
Maigne et al. [13] 1992 26–75 (45.2) Unknown Yes Yes 1-48 M
Benson et al. [14] 2010 25–62 (40.4) More than 6 W Yes Yes 3-42 M(13.2 M)
Komori et al. [15] 1998 20–75 (41) 2-359D(54D) Yes Yes 27-856D(151D)
Modic et al. [16] 1995 22–75 (49.2) Less than 2 W Yes Yes 6 W-6 M
Kamanli et al. [17] 2010 (37) Unknown Unknown No 4-6 W
Autio et al. [18] 2006 19–78 3–28 W Yes Yes 12 M
Gallucci et al. [19] 1995 27–62 (37) Unknown Some Yes 6 M
Ozturk et al. [20] 2006 16–70 Less than 6 M Some Yes 21D
Ahn et al. [21] 2000 17–74 (39) 1–28 M Yes Yes 3-27 M(8.5 M)
Ilkko et al. [22] 1993 35–74 (53) Unknown Some Yes 4.3–6.1Y(5.2Y)
Delauche-Cavallier et al. [23] 1992 20–64 (43) 15D-6 M(2 M) Yes Yes 6-27 M(12.9 M)
Buttermann et al. [24] 2002 18–70 Unknown Yes Yes 18 ± 10&19 ± 9 M
Bozzao et al. [25] 1992 23–65 (52) 1 M-1Y Some Yes 6-15 M(11 M)
Broetz et al. [26] 2008 18–65 5D-2Y(median 5 W) Yes No 3-7D(5D)
Jensen et al. [27] 2006 18–65 (45) 1-3 M Yes Yes 12 M
Henmi et al. [28] 2002 20–50 1-200D Yes Yes 6-12 M
Takada et al. [29] 2001 16–64 (42) 1-14 W Yes Yes 3-24 M(10.3 M)
Cribb et al. [30] 2007 24–73 (45) Unknown Yes No 5-56 M(24 M)
Ellenberg et al. [31] 1993 28–67 (42) Unknown Yes Yes 6-18 M(9.8 M)
Demirel et al. [32] 2017 50.7 Unknown Unknown Yes 3 M
Hong et al. [33] 2016 26–78 (50.2) Unknown Unknown Yes 2-31 M(8.8 M)
Matsubara et al. [34] 1995 16–52 (36) Unknown Yes Yes 3-18 M(9.7 M)
Yukawa et al. [35] 1996 14–69 (39) Unknown Yes Yes 24-42 M(30 M)
Fagerlund et al. [36] 1990 14–49 (35) 6 ± 3 M Unknown Yes 24 M
Kesikburun et al. [37] 2019 39.7–71.5 (54.4) 4.7–7.4 M(6 M) No Yes 12-19 M(17 M)
Teplick et al. [38] 1985 Unknown Unknown Unknown No 3 M-5Y
Shan et al. [39] 2014 20–66 (40) 2 W-6 M Yes Yes 6 M
Shin et al. [40] 2017 (35.8) (2.7 M) Yes Yes 3Y
Komori et al. [41] 1996 18–86 (41) 0.1–8.6 M(1.8 M) Yes Yes 62-1208D(262D)
Saal et al. [42] 1990 Unknown Unknown Yes Yes 8-77 M(25)
Bush et al. [43] 1992 17–72 (41) 1-72 M(4.2 M) Yes Yes 1Y
Iwabuchi et al. [44] 2010 −52 Unknown Yes Yes (4.1 M)
Yu et al. [45] 2014 16–60 (38.7) 3D-10Y(16.5 M) Yes Yes 2-24 M
Lee et al. [46] 2017 39.08 ± 10.19 Unknown Yes Yes 341.38 ± 306.83D
  1. Average values were presented in parentheses and “±”is connected to Mean and SD if available. D Day, M Month, Y Year