Fig. 2From: Gorham-Stout disease successfully treated with sirolimus (rapamycin): a case report and review of the literature(a) Immunopathological examination was positive for vessel marker CD31. (b) Immunopathological examination was positive for vessel marker CD34. (c) Immunohistochemical staining for D2–40, a specific lymphatic marker, was positive in the bone tissue biopsy. (d) Vessel and lymphatic proliferation within necrotic bone tissue (hematoxylin-eosin [HE], 100× magnification). (e) Vessel and lymphatic proliferation within necrotic bone tissue (hematoxylin-eosin [HE], 400× magnification)Back to article page