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Table 4 Diagnostic accuracy, 5PQ compared with the BeS cut-off ≥5. Prevalence adjusted with 10%

From: Validity of the self-reported five-part questionnaire as an assessment of generalized joint hypermobility in early pregnancy

5PQ

Sensitivity % (CI)

Specificity % (CI)

AUC (CI)

PPV % (CI)

NPV % (CI)

LR+ (CI)

≥ 1

97.7 (88.0–99.9)

29.6 (24.1–35.6)

0.64 (0.60–0.67)

13.4 (12.3–14.4)

99.2 (94.4–99.9)

1.4 (1.3–1.5)

≥ 2

84.1 (69.9–93.4)

61.9 (55.6–67.8)

0.73 (0.67–0.79)

19.7 (16.7–23.1)

97.2 (94.6–98.6)

2.2 (1.8–2.7)

≥ 3

61.4 (45.5–75.6)

81.7 (76.4–86.2)

0.72 (0.64–0.79)

27.2 (20.8–34.6)

95.0 (92.9–96.5)

3.4 (2.4–4.8)

≥ 4

38.6 (24.4–54.5)

94.2 (90.6–96.7)

0.66 (0.59–0.74)

42.4 (28.4–57.7)

93.2 (91.6–94.6)

6.6 (3.4–12.3)

≥ 5

4.5 (0.6–15.5)

99.2 (97.2–99.9)

0.52 (0.49–0.55)

39.4 (8.6–81.8)

90.3 (89.8–90.9)

5.8 (0.8–40.4)

  1. 5PQ Five-part-questionnaire, BeS Beighton score, CI Confidence interval, AUC Area under curve, PPV Positive predictive value, NPV Negative predictive value, LR+ Positive Likelihood ratio