Sjogren’s syndrome is associated with higher rate of non-home discharge after primary hip arthroplasty and higher transfusion rates after primary hip or knee arthroplasty: a U.S. cohort study

Table 2 Multivariable-adjusted association of Sjogren’s syndrome with complications and healthcare utilization outcomes after primary THA or primary TKA in the main model and the sensitivity analyses

	Primary TKA		Primary THA
	Main Model^a	Sensitivity analyses^b	Main Model^a	Sensitivity analyses^b
	Odds Ratio (95% CI)	Odds Ratio (95% CI)	Odds Ratio (95% CI)	Odds Ratio (95% CI)
Discharge to a rehabilitation/inpatient facility	0.93 (0.86, 1.02)	0.97 (0.89, 1.06)	1.13 (1.00, 1.28)	1.14 (1.01, 1.30)
Length of hospital stay > 3 days ^c	0.96 (0.88, 1.04)	0.97 (0.89, 1.05)	0.99 (0.88, 1.12)	1.00 (0.89, 1.12)
Total hospital charge above the median ^d	0.98 (0.91,1.06)	0.94 (0.87,1.01)	1.09 (0.98,1.22)	1.05 (0.93,1.17)
In-hospital complications
Transfusion	1.21 (1.10, 1.34)	1.23 (1.12, 1.36)	1.37 (1.22, 1.55)	1.37 (1.21, 1.55)
Infection	1.22 (0.39, 3.78)	1.21 (0.39, 3.78)	1.32 (0.44, 4.01)	1.32 (0.44, 3.92)
Revision	1.41 (0.63, 3.15)	1.39 (0.62, 3.11)	1.72 (0.80, 3.72)	1.73 (0.79, 3.76)
Death	0.98 (0.24, 3.93)	0.99 (0.25, 3.97)	0.85 (0.43, 1.70)	0.86 (0.42, 1.76)

^a Main model was adjusted for socio-demographics (age, race/ethnicity, gender, income), Deyo-Charlson comorbidity index, insurance payer and the underlying diagnosis for primary TKA or primary THA, respectively
^b Sensitivity analyses adjusted each main model additionally for hospital characteristics including hospital location/teaching status, hospital region, and hospital bed size
^c The median length of hospital stay was 2.7 days for TKA and 2.8 days for THA, both rounded off to 3 days
^d Median hospital charges were provided for each calendar year by the NIS:
Primary THA: 1998, $19,717; 1999, $20,514; 2000, $22,333; 2001, $24,189; 2002, $26,729; 2003, $29,858; 2004, $32,607; 2005, $34,615; 2006, $36,164; 2007, $39,675; 2008, $43,064; 2009, $41,602; 2010, $45,186; 2011, $48,898; 2012, $48,927; 2013, $50,827; 2014, $51,482
Primary TKA: 1998, $18,987; 1999, $19,717; 2000, $21,043; 2001, $22,622; 2002, $24,736; 2003, $26,696; 2004, $29,535; 2005, $31,686; 2006, $34,254;2007, $36,356; 2008, $38,920; 2009, $39,681; 2010, $42,191; 2011, $45,616; 2012, $46,438; 2013, $48,248; 2014, $49,330
BOLD indicates significant odds ratio
CI confidence interval

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