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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: MicroRNA-410-3p modulates chondrocyte apoptosis and inflammation by targeting high mobility group box 1 (HMGB1) in an osteoarthritis mouse model

Fig. 1

Identification and verification of candidate HMGB1-associated miRNAs. a, miRNAs that were identified as candidates associated with HMGB1 based on ‘online available bio-informatic tools including PTA, miRmap, microT, miRanda and targetScan. b, qRT-PCR detection of transcript levels after overexpression of the candidate miRNAs miR-410-3p, (c), miR-505-3p and (d), miR-129-5p in mouse primary chondrocytes. E, qRT-PCR detection of transcript levels of HMGB1 with the overexpression of miR-410-3p, (f), miR-505-3p and (g), miR-129-5p. The value of the control was set at ‘1’ in qRT-PCR analysis. *P < 0.05, **P < 0.01 vs NC

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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