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Table 1 The schedule of trial enrolment and assessments

From: Effectiveness of preemptive antifibrinolysis with tranexamic acid in rheumatoid arthritis patients undergoing total knee arthroplasty: a study protocol for a randomized controlled trial

  Study period
Pre-D3 Pre-D1 OP D1 D2 D3 DOD D14 D90
 Eligibility screen         
 Informed consent         
Outcome assessment
 Hemoglobin level      
 Fibrinolysis parameters      
 Inflammatory markers      
 Coagulation parameters      
 Pain level      
 Analgesia usage        
 Knee range of motion    
 Hospitalization costs          
 Adverse events    
  1. Pre-D3, 3 days before surgery; Pre-D1, 1 day before surgery; OP, operative; TBL, total blood loss; IBL, intraoperative blood loss; HBL, hidden blood loss; LOS, length of stay; DVP, deep vein thrombosis; PE, pulmonary embolism; D1, the 1st day after surgery; D2, the 2nd day after surgery; D3, the 3rd day after surgery; DOD, the day of discharge; D14, the 14th day after surgery; D90, the 90th day after surgery