Table 1 The schedule of trial enrolment and assessments

 Eligibility screen

●

 Informed consent

●

 Randomization

●

 TBL

●

●

●

 IBL

●

 HBL

●

●

●

 Hemoglobin level

●

●

●

●

●

●

 Fibrinolysis parameters

●

●

●

●

●

●

 Inflammatory markers

●

●

●

●

●

●

 Coagulation parameters

●

●

●

●

●

●

 Pain level

●

●

●

●

●

●

 Analgesia usage

●

●

●

 Knee range of motion

●

●

●

●

●

●

●

 LOS

●

 Hospitalization costs

●

 DVT

●

●

●

 PE

●

●

●

 Adverse events

●

●

●

●

●

●