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Fig. 4 | BMC Musculoskeletal Disorders

Fig. 4

From: Down-regulation of FTX promotes the differentiation of osteoclasts in osteoporosis through the Notch1 signaling pathway by targeting miR-137

Fig. 4

miR-137 mediated the effects of FTX on osteoclast differentiation. a. qRT-PCR for expressions of TRAP, CTSK, and NFATC1, TRAF6 CD14 + PBMCs. b and c. Cell viability and apoptosis by CCK-8 assays and flow cytometry. d. TRAP-staining photos for osteoclast differentiation under transfection with pcDNA-FTX or pcFTX+miR-137 mimic. e. Representative microscopic pictures of resorption pit*P < 0.001. **P < 0.001, n = 3

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