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Table 5 SF 12-MCS and associated patients’ characteristics and clinical conditions: multivariable generalised estimating equation models

From: Quality of life outcomes in patients undergoing knee replacement surgery: longitudinal findings from the QPro-Gin study

SF 12-MCS Total (n = 132) Rehabilitation program after discharge
Yes (n = 40) No (n = 92)
β 95%CI P β 95%CI P β 95%CI P
Intercept 55.94 50.27,61.61 < 0.001 53.37 38.98,67.76 < 0.001 55.51 50.31,60.72 < 0.001
Time (3-months post-surgery) 2.31 −4.84,9.46 0.527 −7.95 −20.26,4.35 0.205 4.34 −4.19,12.87 0.319
Age ≥ 65 years 3.61 −0.63,7.85 0.095 4.95 −1.94,11.85 0.159 3.64 −1.44,8.71 0.160
Time*Age ≥ 65 years −2.83 −7.73,2.07 0.258 −2.39 −9.31,4.52 0.498 −2.82 −9.07,3.43 0.376
Female sex −3.10 −6.67,0.47 0.089 1.87 −5.27,9.00 0.608 −4.88 −9.13,-0.63 0.024
Time*Female sex −3.39 −7.44,0.65 0.100 −3.93 −11.33,3.48 0.299 −2.16 −7.28,2.96 0.409
Low education −5.35 −8.52,-2.18 0.001 −5.49 −10.60,-0.38 0.035 −6.59 −10.81,-2.36 0.002
Time*Low education 4.32 0.36,8.28 0.033 5.00 −0.49,10.48 0.074 5.80 0.31,11.29 0.038
BMI ≥ 30 kg/m2 0.93 −2.41,4.27 0.586 − 2.22 −7.03,2.58 0.364 1.90 −2.25,6.04 0.369
Time*BMI ≥30 kg/m2 1.16 −3.11,5.43 0.596 4.59 −2.08,11.25 0.177 0.97 −4.60,6.53 0.734
Depressive symptoms −12.41 −16.51,-8.31 < 0.001 −14.51 −20.71,-8.31 < 0.001 − 10.23 − 15.99,-4.47 0.001
Time*Depressive symptoms 3.22 −1.91,8.36 0.219 −0.13 −7.62,7.37 0.974 3.16 −3.80,10.11 0.374
Cognitive impairment 3.86 −2.33,10.05 0.222 11.61 4.03,19.20 0.003 0.73 −6.76,8.22 0.849
Time*Cognitive impairment 0.03 −5.73,5.80 0.992 −4.64 −13.82,4.54 0.322 1.18 −6.16,8.51 0.753
Comorbidity ≥ 4 diseases −3.45 −6.83,-0.07 0.045 −7.02 −13.43,-0.61 0.032 −0.89 −5.26,3.48 0.690
Time*Comorbidity ≥4 diseases 0.35 −3.43,4.13 0.856 6.78 0.23,13.32 0.042 −2.48 −7.58,2.62 0.340
Current smoker −1.02 −5.84,3.80 0.678 3.13 −2.19,8.46 0.249 −1.46 −7.99,5.07 0.662
Time*Current smoker 1.52 −4.86,7.91 0.640 −4.70 −12.15,2.75 0.217 3.82 −4.15,11.79 0.347
Current alcohol user −0.68 −4.55,3.19 0.731 0.30 −7.68,8.28 0.941 −0.36 −4.70,3.98 0.871
Time*Current alcohol user 2.10 −2.69,6.89 0.390 9.09 4.47,13.70 < 0.001 −0.08 −5.85,5.68 0.978
TKA surgery 0.88 −2.54,4.30 0.614 0.84 −5.12,6.79 0.783 1.58 −2.45,5.62 0.442
Time*TKA surgery −3.01 −6.93,0.90 0.132 −2.70 −8.72,3.32 0.380 − 3.95 −9.03,1.13 0.128
  1. Abbreviation: β, coefficient regression, CI confidence intervals, SF-12 Short-Form General Health Survey, MCS mental component scores, BMI Body Mass Index, TKA total knee arthroplasty (reference UKA, unicompartmental knee arthroplasty)
  2. SF 12-MCS ranges from 0 [worst] to 100 [best]