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Table 5 Postoperative complications and clinical outcomes in the BP and TP groups according to whether the cause of OVF was primary osteoporosis or GIOP

From: Effect of bisphosphonates or teriparatide on mechanical complications after posterior instrumented fusion for osteoporotic vertebral fracture: a multi-center retrospective study

 

Primary osteoporosis

GIOP

BP

TP

p-value

BP

TP

p-value

Cases, n

93

39

–

11

16

–

Mechanical complications

67 (72.0%)

24 (61.5%)

0.16

9 (81.8%)

8 (50%)

0.093

New vertebral fracture

42 (45.2%)

15 (38.5%)

0.30

5 (45.5%)

3 (18.8%)

0.14

 Screw complications

39 (41.9%)

15 (38.5%)

0.43

3 (27.3%)

4 (25.0%)

0.90

 Screw loosening

28 (30.1%)

14 (35.9%)

0.54

1 (9.1%)

4 (25.0%)

0.30

 Screw backout

11 (11.8%)

1 (2.6%)

0.08

2 (18.2%)

0

0.076

 Rod fracture

0

0

–

0

0

–

 Pseudoarthrosis

6 (6.5%)

0

0.12

3 (27.3%)

1 (6.3%)

0.13

Revision due to mechanical complications

10 (10.8%)

7 (17.9%)

0.27

0

2 (12.5%)

0.50

Postoperative JOA score

9.9 ± 3.3

9.6 ± 3.7

0.75

9.3 ± 3.2

8.3 ± 3.0

0.49

JOA score recovery rate

49.2 ± 30.1

54.4 ± 25.9

0.32

48.0 ± 19.8

44.7 ± 26.3

0.69

Final VAS (back pain)

30.9 ± 23.7

29.8 ± 26.0

0.95

27.2 ± 20.1

36.2 ± 20.3

0.30

Change in VAS (back pain)

40.5 ± 30.9

40.3 ± 32.1

0.98

40.3 ± 26.7

38.7 ± 33.6

0.90

Final VAS (leg pain or numbness)

18.9 ± 21.4

19.9 ± 24.8

0.81

15.0 ± 14.7

28.9 ± 28.2

0.15

Change in VAS (leg pain or numbness)

34.7 ± 28.9

34.9 ± 31.9

0.87

29.2 ± 20.9

39.9 ± 25.1

0.28

  1. BP bisphosphonate, TP teriparatide, GIOP glucocorticoid-induced osteoporosis, JOA Japanese Orthopaedic Association, VAS visual analogue scale