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Table 2 Preoperative demographic and clinical characteristics according to whether osteoporosis medication was BP or TP

From: Effect of bisphosphonates or teriparatide on mechanical complications after posterior instrumented fusion for osteoporotic vertebral fracture: a multi-center retrospective study

 

BP

TP

p-value

Cases, n

104

55

–

Age at surgery, years

75.2 ± 6.8

76.4 ± 6.4

0.46

Sex (female)

89 (85.6%)

47 (85.5%)

0.98

BMI

22.2 ± 4.8

22.6 ± 5.7

0.62

Smoking history

14 (13.5%)

6 (10.9%)

0.64

Number of previous vertebral fractures

0.4 ± 0.89

0.6 ± 1.0

0.20

Number of new vertebral fracture

1.0 ± 0.2

1.1 ± 0.3

0.13

Time from injury to surgery (days)

183 ± 275

152 ± 154

0.44

BMD, YAM%

72.5 ± 17.7

73.0 ± 13.9

0.87

Preoperative drug use for osteoporosis

38 (36.5%)

33 (60.0%)

0.007

 BP

32 (30.8%)

23 (41.8%)

0.22

 Vit D

7 (6.7%)

7 (12.7%)

0.24

 TP

0

7 (12.7%)

< 0.001

Number of fixed levels

3.0 ± 0.8

3.2 ± 0.8

0.21

Preoperative JOA score

4.8 ± 3.6

4.1 ± 3.3

0.15

Preoperative VAS (back pain)

71.2 ± 22.9

74.6 ± 27.1

0.25

Preoperative VAS (leg pain or numbness)

53.1 ± 31.6

58.4 ± 32.9

0.36

  1. BP bisphosphonate, TP teriparatide, BMI body mass index, BMD bone mineral density, YAM young adult mean, Vit D vitamin D, JOA Japanese Orthopaedic Association, VAS visual analogue scale