The risk of fracture and prevalence of osteoporosis is elevated in patients with idiopathic inflammatory myopathies: cross-sectional study from a single Hungarian center

Table 3 Clinical and laboratory data of myositis and RA patients with and without fractures

Characteristics of myositis patients	With fracture N = 30		Without fracture N = 10		P-value
Characteristics of myositis patients	Mean^a/Median^b	SD^a/Min-Max^b	Mean^a/Median^b	SD^a/Min-Max^b	P-value
Age (years)^a	62.83	9.858	55.4	9.057	0.034
Duration (years)^b	13.5	1–28	9.5	1–21	0.16
Cumulative steroid (g)^b	20.2	0–135.4	14.6	0.2–71.3	0.79
BMD L1–4 (g/cm²) ^b	1.08	0.79–1.54	1.04	0.84–1.15	0.20
BMD femur (g/cm²) ^b	0.82	0.62–1.05	0.84	0.67–1.02	0.76
25OH-Vitamin D3 level (nmol/L)^b	57.4	27.8–125.2	66.2	24.2–90	0.61
ß-CTx (ug/L) ^b	0.28	0.05–0.81	0.21	0.1–0.46	0.43
Characteristics of RA patients	With fracture N = 24		Without fracture N = 11		P-value
Age (years)^a	63.25	9.175	52	11.610	0.022
Duration (years) ^b	6.5	1–29	7	1–26	0.97
Cumulative steroid (g)^b	4	0–55	4.3	0–28	0.430
BMD L1–4 (g/cm²)^b	1.00	0.85–1.42	1.19	1–1.41	0.008
BMD femur (g/cm²)^b	0.83	0.7–1.02	0.94	0.84–1.11	0.010
25OH-Vitamin D3 level (nmol/L) ^b	69.0	29.2–129.2	53.2	27.5–85.5	0.11
ß-CTx (ug/L) ^b	0.26	0.07–0.57	0.22	0.07–0.45	0.3

Duration of the disease in years, BMD L1–4 Bone Mineral Density from the lumbar 1–4 vertebrae, BMD femur Bone Mineral Density in the left femoral neck, ß-CTx beta-crosslaps
Significances were calculated with independent samples t-test or Mann-Whitney test, according to the distribution. Normality of the distributions was checked using Shapiro-Wilk test. Data are presented as mean and standard deviation (SD) with normal distribution (a on the upper corner of the variable) and median, minimum, maximum with non-gaussian distribution (b on the upper corner of the variable). Stepwise discriminant analysis (Wilks) was also performed, data are found in the text

ISSN: 1471-2474