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Table 1 Summary of the most relevant clinical data and FRAX scores of the patients

From: The risk of fracture and prevalence of osteoporosis is elevated in patients with idiopathic inflammatory myopathies: cross-sectional study from a single Hungarian center

 

Myositis

N = 52

Rheumatoid arthritis

N = 43

P-value

(95% CIoD)

 

Meana/Medianb

SDa/Min-Maxb

Meana/Medianb

SDa/Min-Maxb

 

Age (years)a

57.46

11.168

58.58

10.486

0.618 (−5.6–3.3)

Men (N)

Women (N)

9 (17.3%)

43 (82.7%)

 

2 (4.7%)

41 (95.3%)

 

0.104

Menopause at examination (N)

33/43 (76.67%)

 

35/41% (85.3%)

 

0.314

Weight (kg)a

70.88

14.38

73.74

13.77

0.328 (−2.9–2.9)

Height (cm) a

164.12

7.56

163.7

7.1

0.308

(0.4–1.5)

BMI (kg/m2) a

26.39

5.58

27.5

4.6

0.318

(−1.1–1.1)

Vitamin D and calcium supplement (N)

34 (65.4%)

 

29 (67.4%)

 

0,833

25 OH Vitamin D3 level (nmol/L) b

59.5

15.2–125.2

62.5

27.5–129.2

0.196

BMD L1–4 (g/cm2)a

1.04

0,238

1.07

0.159

0.557 (−0.08–0.07)

BMD femur (g/cm2) a

0.83

0,108

0.85

0.125

0.294 (−0.09–0.01)

Normal (N)

14 (27%)

 

23 (53.5%)

 

0.045

Osteopenia (N)

31 (60%)

 

17 (39.5%)

 

Osteoporosis (N)

7 (13.5%)

 

3 (7%)

 

FRAX score: MOF

Without DEXA1a

9.68%

7.42

15.58%

10.91

0.008

 With DEXA2a

9.44%

6.723

13.25%

9.43

0.053

 Steroid dose adjusted with DEXA3a

9.54%

7.475

9.96%

7.968

0.884

FRAX score: HF

Without DEXA1a

3.06%

3.97

6.23%

7.20

0.022

 With DEXA2a

2.77%

3.01

3.57%

5.08

0.811

 Steroid dose adjusted with DEXA3a

2.87%

3.393

2.46%

3.382

0.128

  1. BMI body mass index, BMD L1–4 Bone Mineral Density from lumbal 1–4 vertebrae, BMD femur Bone Mineral Density in the left femoral neck, Normal-Osteopenia-Osteoporosis: the condition of the bone according to the T-score result, FRAX Fracture Risk Assessment Tool, MOF Major Osteoporotic Fracture, HF Hip Fracture, DEXA dual-energy x-ray absorptiometry
  2. Significances were calculated with independent samples t-test or Mann-Whitney test, according to the distribution. Normality of the distributions was checked using Shapiro-Wilk test. Data are presented as mean and standard deviation (SD) with normal distribution (a on the upper corner of the variable) and median, minimum, maximum with non-gaussian distribution (b on the upper corner of the variable); 95% CIoD: 95% Confidence Interval of the Difference (lower-upper). Categorical variables were described using frequency (case number) and percentage. FRAX scores were calculated 1: without the DEXA levels and without steroid dose adjustment (steroid yes/no only); 2: With DEXA levels without steroid dose adjustment (steroid yes/no only); 3: With DEXA levels and steroid dose adjustment