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Table 3 Postoperative comparison of LIN and ULN

From: Distal locked versus unlocked intramedullary nailing for stable intertrochanteric fractures, a systematic review and meta-analysis

Studies No. of studies Patients (N) Distal locking (events/total) Distal unlocking (events/total) Heterogeneity (I2, P) Result OR /MD, 95%CI,P
Total complications
 RCT subgroup 2 261 73/258 50/190 I2 = 0%, P = 0.90 1.40 [0.90, 2.19] P = 0.14
 Non-RCT subgroup 2 448 20/112 21/149 I2 = 0%, P = 0.34 1.28 [0.65, 2.51] P = 0.06
 Overall 4 709 93/370 71/339 I2 = 0%, P = 0.88 1.36 [0.94, 1.98] P = 0.10
Haematoma 3 537 11/298 8/239 I2 = 0%, P = 0.78 1.13 [0.44, 2.90] P = 0.80
Deep Vein Thrombosis 3 537 3/298 2/239 I2 = 0%, P = 0.98 1.18 [0.22, 6.26] P = 0.85
Cutting out
 RCT subgroup 4 714 6/388 3/326 I2 = 0%, P = 0.96 1.51 [0.37, 6.25] P = 0.57
Non-RCT subgroup 4 415 2/186 1/229 I2 = 41%, P = 0.90 1.52 [0.26, 8.99] P = 0.64
Overall 8 1129 8/574 4/555 I2 = 0%, P = 0.64 1.52 [0.50, 4.60] P = 0.46
Loss of reduction
 RCT subgroup 3 655 3/421 5/399 I2 = 43%, P = 0.19 0.66 [0.08, 5.76] P = 0.71
 Non-RCT subgroup 2 165 3/359 5/296 N/A N/A
 Overall 5 820 0/62 0/103 I2 = 43%, P = 0.19 0.66 [0.08, 5.76] P = 0.71
Peri-implant fractures
 RCT subgroup 4 714 6/388 8/326 I2 = 60%, P = 0.11 0.50 [0.06, 4.23] P = 0.52
 Non-RCT subgroup 4 1157 5/725 18/432 I2 = 78%, P = 0.004 0.73 [0.05, 11.03] P = 0.82
 Overall 8 1871 11/1113 26/758 I2 = 69%, P = 0.006 0.59 [0.11, 3.18] P = 0.54
Wound infection 4 714 12/388 13/326 I2 = 0%, P = 0.80 0.76 [0.34, 1.67] P = 0.49
Deep infection 4 714 3/388 0/326 N/A 7.00 [0.36, 137.53] P = 0.20
Delayed union
 RCT subgroup 4 714 5/388 3/326 I2 = 41%, P = 0.18 1.53 [0.43, 5.43] P = 0.51
 Non-RCT subgroup 3 308 0/130 1/178 N/A 0.51 [0.02, 13.29] P = 0.69
 Overall 7 1022 5/518 4/504 I2 = 30%, P = 0.19 1.30 [0.41, 4.13] P = 0.65
Non-union 3 272 0/298 1/239 N/A 0.35 [0.01, 8.57] P = 0.52
Avascular necrosis of the femoral head
 RCT subgroup 3 655 1/359 2/296 I2 = 0%, P = 0.82 0.41 [0.05, 3.30] P = 0.40
 Non-RCT subgroup 3 368 0/168 2/200 I2 = 0%, P = 0.79 0.40 [0.04, 3.93] P = 0.43
 Overall 6 1023 1/527 4/496 I2 = 0%, P = 0.99 0.41 [0.09, 1.90] P = 0.25
Thigh pain
 RCT subgroup 3 502 49/249 16/253 I2 = 63%, P = 0.07 2.90 [0.97, 8.68] P = 0.06
 Non-RCT subgroup 3 272 7/118 6/154 I2 = 20%, P = 0.29 1.62 [0.37, 7.04] P = 0.52
 Overall 6 774 55/367 22/407 I2 = 45%, P = 0.10 2.45 [1.05, 5.73] P = 0.04