Skip to main content

Table 2 Acute and 12-week outcomes by pre-surgical opioid use status

From: Associations between pre-surgical daily opioid use and short-term outcomes following knee or hip arthroplasty: a prospective, exploratory cohort study

 Non-opioid
N = 439 max
Opioid user
N = 82 max
P-value
Oral morphine equivalent dose, mean
 log3.814.19<  0.001
 Daily, mg53.2 (36)87.2 (81.2)<  0.001
 Total, mg227 (174)406 (329)<  0.001
LOS, days, mean (SD)4.7 (2.4)5.1 (2.8)0.218
Referral to inpatient rehabilitation, n (%)36 (8.2)12 (14.8)0.059
Acute complications, n (%)80 (18.2)23 (28.1)0.040
 Major joint9 (2.1)1 (1.2)1.000
 Minor joint35 (8.0)10 (12.2)0.210
 Major non-joint11 (2.5)4 (4.9)0.240
 Minor non-joint35 (8.0)13 (15.9)0.024
Cost of investigations, $
 median (IQR)156.55 (143)189.80 (230)0.003
 mean (SD)232.62 (260)316.81 (329)0.033
Complications or readmissions to 12 weeks, n (%)167 (38.0)35 (42.7)0.428
(Readmissions)(31 (7.1))(9 (11.0)) 
Oxford score 12 weeks, n (%) in lower quartilea96 (25.7)18 (26.1)0.950
Oxford scorec, mean (SD), 12 weeksa37.4 (7.4)36.1 (7.4)0.182
EQVAS 12 weeks, n (%) in lower quartileb92 (25.1)23 (33.8)0.130
EQVASd mean (SD) 12 weeksb75.2 (17.6)71.6 (18.8)0.133
Ongoing opioids at 12 -weeks, any reason, n (%)
(for index joint joint)
39 (9.2)
(32) (82.0)
27 (33.8)
(17) (63.0)
<  0.001
  1. a15% of the data missing; b 17% of the data missing; $ = Australian dollars; chigher scores are better (maximum 48); dHigher score is better (maximum 100)