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Table 4 Odd ratios of variables in rheumatic patients with osteopenia and osteoporosis

From: Prevalence and risk factors for bone loss in Southern Chinese with rheumatic diseases

Variables

Osteopenia

Osteoporosis

OR (95% CIs)

P

OR (95% CIs)

P

Former or current chronic GC therapy

N = 163

N = 276

Agea

1.07 [1.03;1.11]

0.001

1.13 [1.08;1.18]

< 0.001

Disease durationb

1.06 [1.00;1.12]

0.033

1.05 [1.00;1.11]

0.052

BMI, Kg/m2

  < 18.5 (underweight)

1.74 [0.44;12.6]

0.469

2.98 [0.83;20.7]

0.102

 18.5–23.9 (normal)

Ref.

Ref.

Ref.

Ref.

 24–27.9 (overweight)

0.54 [0.26;1.11]

0.092

0.30 [0.15;0.61]

0.001

  ≥ 28(obese)

0.55 [0.18;1.93]

0.329

0.17 [0.05;0.65]

0.011

Gender, compared with male

 Female

3.08 [1.55;6.15]

0.001

3.52 [1.83;6.74]

< 0.001

Menopause status

 Post-menopause

Ref.

Ref.

Ref.

Ref.

 Early menopause, age ≤ 45

0.96 [0.32;3.65]

0.943

1.09 [0.39;4.02]

0.877

Medical history

 Diabetes Mellitus

0.84 [0.34;2.28]

0.709

0.71 [0.31;1.88]

0.471

 Hypertension

1.31 [0.62;3.01]

0.492

1.17 [0.57;2.63]

0.675

 Dyslipidemia

0.29 [0.13;0.66]

0.003

0.45 [0.22;0.93]

0.031

 Hyperuricemia

0.58 [0.27;1.30]

0.178

0.42 [0.20;0.92]

0.032

Former or current smokers

0.42 [0.16;1.15]

0.089

0.44 [0.19;1.12]

0.083

Regular drinking

0.48 [0.13;1.97]

0.284

0.65 [0.22;2.40]

0.477

Hypovitaminosis D

2.49 [1.29;4.90]

0.007

3.95 [2.09;7.58]

< 0.001

CRP elevation

1.15 [0.60;2.22]

0.673

1.60 [0.85;2.99]

0.143

ESR elevation

1.36 [0.68;2.67]

0.374

2.49 [1.27;4.80]

0.009

Non-GC therapy

N = 176

N = 239

Agea

1.12 [1.09;1.16]

< 0.001

1.16 [1.12;1.20]

< 0.001

Disease durationb

1.02 [0.98;1.06]

0.311

1.02 [0.99;1.06]

0.128

BMI, Kg/m2

  < 18.5 (underweight)

0.86 [0.25;3.54]

0.826

2.04 [0.74;7.35]

0.178

 18.5–23.9 (normal)

Ref.

Ref.

Ref.

Ref.

 24–27.9 (overweight)

0.70 [0.40;1.23]

0.217

0.29 [0.16;0.51]

< 0.001

  ≥ 28(obese)

0.54 [0.26;1.14]

0.104

0.29 [0.14;0.60]

0.001

Gender, compared with male

 Female

1.02 [0.48;2.09]

0.949

9.34 [5.51;16.2]

< 0.001

Menopause status

 Post-menopause

Ref.

Ref.

Ref.

Ref.

 Early menopause, age ≤ 45

1.70 [0.43;12.3]

0.485

1.09 [0.39;4.02]

0.877

Medical history

 Diabetes Mellitus

0.97 [0.50;1.93]

0.921

1.02 [0.55;1.99]

0.939

 Hypertension

1.58 [0.92;2.75]

0.098

1.17 [0.69;2.00]

0.566

 Dyslipidemia

0.87 [0.47;1.64]

0.651

0.60 [0.33;1.13]

0.114

 Hyperuricemia

0.66 [0.37;1.16]

0.146

0.54 [0.31;0.93]

0.027

Former or current smokers

0.33 [0.16;0.66]

0.002

0.35 [0.18;0.66]

0.001

Regular drinking

0.29 [0.13;0.61]

0.001

0.24 [0.12;0.51]

< 0.001

Hypovitaminosis D

0.88 [0.51;1.50]

0.639

1.02 [0.60;1.69]

0.95

CRP elevation

0.77 [0.46;1.26]

0.292

0.78 [0.48;1.25]

0.294

ESR elevation

0.83 [0.49;1.40]

0.492

1.48 [0.87;2.48]

0.146

  1. acontinuous variable; bcontinuous variable and correlative with age