From: Prevalence and risk factors for bone loss in Southern Chinese with rheumatic diseases
Variables | Osteopenia | Osteoporosis | ||
---|---|---|---|---|
OR (95% CIs) | P | OR (95% CIs) | P | |
Former or current chronic GC therapy | N = 163 | N = 276 | ||
Agea | 1.07 [1.03;1.11] | 0.001 | 1.13 [1.08;1.18] | < 0.001 |
Disease durationb | 1.06 [1.00;1.12] | 0.033 | 1.05 [1.00;1.11] | 0.052 |
BMI, Kg/m2 | ||||
  < 18.5 (underweight) | 1.74 [0.44;12.6] | 0.469 | 2.98 [0.83;20.7] | 0.102 |
 18.5–23.9 (normal) | Ref. | Ref. | Ref. | Ref. |
 24–27.9 (overweight) | 0.54 [0.26;1.11] | 0.092 | 0.30 [0.15;0.61] | 0.001 |
  ≥ 28(obese) | 0.55 [0.18;1.93] | 0.329 | 0.17 [0.05;0.65] | 0.011 |
Gender, compared with male | ||||
 Female | 3.08 [1.55;6.15] | 0.001 | 3.52 [1.83;6.74] | < 0.001 |
Menopause status | ||||
 Post-menopause | Ref. | Ref. | Ref. | Ref. |
 Early menopause, age ≤ 45 | 0.96 [0.32;3.65] | 0.943 | 1.09 [0.39;4.02] | 0.877 |
Medical history | ||||
 Diabetes Mellitus | 0.84 [0.34;2.28] | 0.709 | 0.71 [0.31;1.88] | 0.471 |
 Hypertension | 1.31 [0.62;3.01] | 0.492 | 1.17 [0.57;2.63] | 0.675 |
 Dyslipidemia | 0.29 [0.13;0.66] | 0.003 | 0.45 [0.22;0.93] | 0.031 |
 Hyperuricemia | 0.58 [0.27;1.30] | 0.178 | 0.42 [0.20;0.92] | 0.032 |
Former or current smokers | 0.42 [0.16;1.15] | 0.089 | 0.44 [0.19;1.12] | 0.083 |
Regular drinking | 0.48 [0.13;1.97] | 0.284 | 0.65 [0.22;2.40] | 0.477 |
Hypovitaminosis D | 2.49 [1.29;4.90] | 0.007 | 3.95 [2.09;7.58] | < 0.001 |
CRP elevation | 1.15 [0.60;2.22] | 0.673 | 1.60 [0.85;2.99] | 0.143 |
ESR elevation | 1.36 [0.68;2.67] | 0.374 | 2.49 [1.27;4.80] | 0.009 |
Non-GC therapy | N = 176 | N = 239 | ||
Agea | 1.12 [1.09;1.16] | < 0.001 | 1.16 [1.12;1.20] | < 0.001 |
Disease durationb | 1.02 [0.98;1.06] | 0.311 | 1.02 [0.99;1.06] | 0.128 |
BMI, Kg/m2 | ||||
  < 18.5 (underweight) | 0.86 [0.25;3.54] | 0.826 | 2.04 [0.74;7.35] | 0.178 |
 18.5–23.9 (normal) | Ref. | Ref. | Ref. | Ref. |
 24–27.9 (overweight) | 0.70 [0.40;1.23] | 0.217 | 0.29 [0.16;0.51] | < 0.001 |
  ≥ 28(obese) | 0.54 [0.26;1.14] | 0.104 | 0.29 [0.14;0.60] | 0.001 |
Gender, compared with male | ||||
 Female | 1.02 [0.48;2.09] | 0.949 | 9.34 [5.51;16.2] | < 0.001 |
Menopause status | ||||
 Post-menopause | Ref. | Ref. | Ref. | Ref. |
 Early menopause, age ≤ 45 | 1.70 [0.43;12.3] | 0.485 | 1.09 [0.39;4.02] | 0.877 |
Medical history | ||||
 Diabetes Mellitus | 0.97 [0.50;1.93] | 0.921 | 1.02 [0.55;1.99] | 0.939 |
 Hypertension | 1.58 [0.92;2.75] | 0.098 | 1.17 [0.69;2.00] | 0.566 |
 Dyslipidemia | 0.87 [0.47;1.64] | 0.651 | 0.60 [0.33;1.13] | 0.114 |
 Hyperuricemia | 0.66 [0.37;1.16] | 0.146 | 0.54 [0.31;0.93] | 0.027 |
Former or current smokers | 0.33 [0.16;0.66] | 0.002 | 0.35 [0.18;0.66] | 0.001 |
Regular drinking | 0.29 [0.13;0.61] | 0.001 | 0.24 [0.12;0.51] | < 0.001 |
Hypovitaminosis D | 0.88 [0.51;1.50] | 0.639 | 1.02 [0.60;1.69] | 0.95 |
CRP elevation | 0.77 [0.46;1.26] | 0.292 | 0.78 [0.48;1.25] | 0.294 |
ESR elevation | 0.83 [0.49;1.40] | 0.492 | 1.48 [0.87;2.48] | 0.146 |