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Table 1 Demographic characteristics of participants

From: Prevalence and risk factors for bone loss in Southern Chinese with rheumatic diseases

  HC RA Pa OA Pa SLE Pa SSc Pa
N = 302 N = 559   N = 198   N = 206   N = 53  
Age, years, median [IQR] 63.0 [53.2;72.8] 58.0 [50.0;66.0] < 0.001 61.0 [53.0;69.8] 0.188 45.0 [35.0;54.0] < 0.001 54.0 [45.0;59.0] < 0.001
Disease durationb, years, median [IQR] NA 5.6 [2.0;12.0] NA 4.0 [1.5;10.0] NA 3.0 [1.0;7.0] NA 3.5 [2.0;7.0] NA
Age groups, years, n(%)    < 0.001   0.008   < 0.001   0.019
  < 30 19 (6.3) 10 (1.8)   2 (1.0)   37 (18.0)   2 (3.8)  
 31–39 9 (3.0) 24 (4.2)   4 (2.0)   38 (18.4)   5 (9.4)  
 40–49 25 (8.3) 105 (18.8)   29 (14.6)   50 (24.3)   10 (18.9)  
  ≥ 50 249 (82.5) 420 (75.1)   163 (82.3)   81 (39.3)   36 (67.9)  
BMI, Kg/m2, mean (SD) 22.5 (3.7) 21.9 (3.5) 0.321 24.1 (4.0) < 0.001 22.0 (3.6) 0.085 21.8 (3.0) 0.935
Gender, female, n(%) 229 (75.8) 450 (80.5) 0.173 165 (83.3) 0.087 187 (90.8) < 0.001 38 (71.7) 0.676
Menopause status of female, n(%)    0.01   0.277   < 0.001   0.067
 Post-menopause 202 (88.2) 359 (79.8)   139 (84.2)   91 (48.7)   29 (76.3)  
 Early menopause, age ≤ 45 31 (15.3) 48 (13.4)   18 (12.9)   18 (19.8)   4 (13.8)  
  HC AS Pa pSS Pa Gout Pa MCTD Pa
  N = 302 N = 128   N = 98   N = 111   N = 45  
Age, years, median [IQR] 63.0 [53.2;72.8] 36.5 [27.0;45.2] < 0.001 54.5 [46.0;60.0] < 0.001 61.0 [48.0;72.0] 0.269 56.0 [46.0;62.0] < 0.001
Disease durationb, years, median [IQR] NA 6.5 [3.0;12.0] NA 1.2 [0.6;2.3] NA 6.0 [3.0;11.5] NA 1.3 [0.5;4.5] NA
Age groups, years, n(%)    < 0.001   0.003   0.006   0.003
  < 30 19 (6.3) 42 (32.8)   5 (5.1)   5 (4.5)   2 (4.4%)  
 31–39 9 (3.0) 30 (23.4)   10 (10.2)   7 (6.31)   2 (4.4)  
 40–49 25 (8.3) 36 (28.1)   17 (17.3)   22 (19.8)   13 (28.9)  
  ≥ 50 249 (82.5) 20 (15.6)   66 (67.3)   77 (69.4)   28 (62.2)  
BMI, Kg/m2, mean (SD) 22.5 (3.7) 22.0 (4.2) 0.865 21.3 (2.9) 0.094 24.1 (3.3) 0.003 21.6 (3.0) 0.79
Gender, female, n(%) 229 (75.8) 40 (31.2) < 0.001 91 (92.9) 0.001 18 (16.2) < 0.001 39 (86.7) 0.197
Menopause status of female, n(%)    < 0.001   0.001   0.734   0.001
 Post-menopause 202 (88.2) 9 (22.5)   66 (72.5)   17 (94.4)   26 (66.7)  
 Early menopause, age ≤ 45 31 (15.3) 3 (33.3)   5 (7.6)   5 (29.4)   7 (26.9)  
  1. aCompared with healthy controls. b:correlated with age
  2. HC healthy controls, RA rheumatoid arthritis, OA osteoarthritis, SLE systemic lupus erythematosus, SSc systemic scleroderma, AS ankylosing spondylitis, pSS primary Sjogren syndrome, MCTD mixed connective tissue disease