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Table 2 Frequency of Accelerated or Rapid KOA Using Previously Reported Definitions Among Adults without Radiographic KOA at OAI Baseline

From: Risk factors and the natural history of accelerated knee osteoarthritis: a narrative review

Term Radiographic Change Time Frame Incidence in OAI
Accelerated OA [1, 3, 4] KL 0 or 1 to KL 3 or 4 4 or 5 years 7.2%
Rapid Radiographic Change [47] KL 0 or 1 then KL change > 2 4 or 5 years 12.4%
Fast JSW Loss [48] > 0.25 mm medial JSW change 1 year 15.5 to 22.1%
Rapid Progressors [49] > 1.05 mm medial JSW change 1 year 0.4 to 0.8%
Rapid Destructive Arthrosis [50] > 2 mm JSW change or 50% narrowing 1 year 0%
Rapid Progressive OA Type 1 [46, 47] > 2.00 mm JSW change 1 year 0%
Rapid Progressive OA Type 2 [46, 47] abnormal bone loss or destruction short period of time 0%
  1. Note: KOA  knee osteoarthritis, OAI  Osteoarthritis Initiative, OA  osteoarthritis, JSW  joint space width