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Table 3 Effect of OVX and OVXG on the lipidome of sheep in the short-term approach

From: Effects of short- and long-term glucocorticoid-induced osteoporosis on plasma metabolome and lipidome of ovariectomized sheep

m/z Lipid class OVX vs Control OVXG vs OVX p
FC FC FC FC
1 2 1 2 Trt Time Int
735.521 PG 33:0 1.08 0.91 1.01 1.01 0.002 0.075 0.003
752.511 CL 76:7 1.11 1.00 1.01 0.83 0.004 0.003 0.013
726.496 CL 72:5 1.08 1.02 1.00 0.96 0.005 0.011 0.016
785.429 PI 31:5 1.15 0.98 0.99 0.87 0.011 0.01 0.028
557.236 PI 14:0 1.23 0.94 1.02 0.82 0.035 0.104 0.038
  1. Relative intensities were measured in plasma samples of control group (n = 10), OVX group (n = 12) and OVXG (n = 6) using linear mixed models. Results are fold changes (FC) of the lipid intensities between the OVX and control groups and between the OVXG and the OVX groups at month one and month two, among identified compounds by LC-MS. FC with a value > 1 indicated a relatively higher intensity present in treated animals, whereas a value < 1 indicated a relatively lower intensity compared with their respective control animals
  2. PG phosphatidylglycerol, CL cardiolipin, PI phosphatidylinositol