Fig. 2From: Composite quantitative knee structure metrics predict the development of accelerated knee osteoarthritis: data from the osteoarthritis initiativeComposite Structural Metrics that Conceptualize Knee Osteoarthritis Progression as the Combination of Cumulative Damage and Disease Activity. Parsimonious semi-automated programs were used to individually assess cartilage damage index, bone marrow lesion volume, and effusion-synovitis. Cumulative damage is the sum of standardized cartilage damage (four regions: medial/lateral tibia/femur). Disease activity is the sum of the standardized volumes of effusion-synovitis (single volumetric measure) and BML (four regions: medial/lateral tibia/femur)Back to article page