Skip to main content

Table 1 Incidence rate and risk factors in previous literature

From: Incidence and risk factors of spinal epidural hemorrhage after spine surgery: a cross-sectional retrospective analysis of a national database

Authors

Year

Incidence (cases/total population)

Risk factors

P-value

Kou et al. [27]

2002

NA

Multilevel procedure

0.037

Anno et al. [28]

2019

0.42% (14/3371)

Presence of preoperative coagulopathy

< 0.001

  

Cervical: 0.47% (4/856)

Age

NA

  

Thoracic: 0.60% (2/332)

Multilevel procedure

NA

  

Lumbar: 0.37% (8/2183)

Scar tissue due to previous spinal surgery

NA

   

Heparinization

NA

   

Vessel damage

NA

Kebaish et al. [29]

2004

0.2%

NA

NA

Yamada et al. [30]

2015

0.39% (32/8250)

≥ 50 mmHg increase in blood pressure after extubation

0.03

   

Obesity

0.018

Agnelli et al. [31]

1999

0% (0/15)

  

Gerlach et al. [32]

2004

0.7% (13/1954)

Thrombocytopenia

NA

   

Anticoagulant use

NA

   

Antiplatelet agent use

NA

   

Alcohol consumption

NA

   

Coagulopathy

NA

   

Malignancy

NA

Uribe et al. [33]

2003

0.22% (9/4018)

Thrombocytopenia

NA

   

Coagulation factor deficiency

NA

   

Medications that predispose to bleeding

NA

   

Previous surgery with attendant scarring at the site of epidural hematoma

NA

   

Diabetes

 

Kim et al. [34]

2019

23.6% (94/304; diagnosed by MRI)

Anticoagulant use

< 0.001

  

1.97% (6/304; hematoma evacuation surgery)

Female sex

0.012

   

Old age (>  70 years)

0.025

   

Use of intraoperative water infusion pump

0.003

   

Type of operation

0.01

Ohba et al. [35]

2017

0.468% (6/1282)

Hypertension

NA

   

Age > 60 years

NA

   

Anticoagulant use

NA

   

Use of nonsteroidal anti-inflammatory drugs (NSAIDs)

NA

   

Previous spine surgery

NA

   

Multilevel procedure

NA

   

Blood loss > 1 L

NA

   

Infections

NA

Goldstein et al. [36]

2013

1.5% (8/529)

Use of nonsteroidal anti-inflammatory drugs (NSAIDs)

0.24

   

Increase in Charlson Comorbidity Index

0.003

Yi et al. [37]

2006

0.28% (9/3270)

Coagulopathy

 
   

Anticoagulant use

 
   

Cancer

 

Thiele et al. [38]

2008

NA

Predisposed bleeding

NA

   

Prolonged surgical time

NA

   

Old age

NA

   

Trauma

NA

Knusel et al. [39]

2019

0.27% (206/75,878)

Old age

NA

   

Obesity (BMI > 35)

NA

   

Transfusion

NA

   

Multilevel procedure

NA

   

Invasive procedure

NA

   

Microscope use

NA

  1. NA not available