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Table 6 Pooled estimates of association of IL-6 174G/C and osteoporosis risk, only studies with matching, and studies conforming to HWE

From: Association of IL-6 174G/C (rs1800795) and 572C/G (rs1800796) polymorphisms with risk of osteoporosis: a meta-analysis

Genetic Model Test of association Tests for heterogeneity
OR (95%CI) Ph P value I2
IL-6 174G/C
G VS C 1.07 (0.82–1.39) 0.618 0.018 63.30%
CC VS GG 1.05 (0.71–1.57) 0.805 0.217 30.60%
GC + CC VS GG 1.01 (0.73–1.41) 0.942 0.05 57.80%
CC VS GG + GC 0.93 (0.65–1.34) 0.692 0.194 32.20%