Fig. 1

In vivo FMT. a FMT scan of an F8-KO, sham and WT mouse imaged 24 h after induced joint bleed. VOIs are drawn around both knee joints; colour-bar indicates signal concentration in the VOI. b Relative (ΔFMT) and absolute (c) fluorescent signal in the injured (or left; sham) or contralateral (d) knees of F8-KO, sham and WT mice over time (mean +/− standard error of the mean). e: 24 h ΔFMT in the three groups (mean +/− standard deviation). Statistical differences between F8-KO and sham or WT mice are marked with # or *, respectively. Statistical significance levels are marked: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001