Is Procalcitonin (PCT) a reliable biomarker for preoperative diagnosing of low grade periprosthetic joint infection? A prospective study

Table 2 Procalcitonin: Overview of sensitivity and specificity values in different studies

Author	Parameter	Cut-Off	Sensitivity	Specifity	p-value
Current study	Serum PCT	0.5 ng/ml	13	91	< 0.001
	Synovial fluid PCT	1.0 ng/mL	87	0
	Synovial fluid PCT	5.0 ng/mL	13	52
Glehr et al. (2013) [8]	Serum PCT	0.055 ng/mL	81	54	0.038
Glehr et al. (2013) [8]	Serum PCT	0.36 ng/mL	90	33	0.038
Randau et al. (2014) [21]	Serum PCT	46 ng/mL	13	100
Sa-Ngasoong-song P et al. (2019) [15]	Serum PCT	0.1 ng/mL	65	92	< 0.001
		0.3 ng/mL	50	100
		0.5 ng/mL	40	100
	Synovial fluid PCT	0.08 ng/mL	90	83	< 0.001
		0.12 ng/mL	80	92
		0.16 ng/mL	55	91
Bottner et al. (2007) [40]	Serum PCT	0.3 ng/mL	33	98	n.a.

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