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Table 3 Improvement rate from baseline to 12-month postoperatively in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), visual analog scale (VAS) for pain, Japanese Knee Osteoarthritis Measure (JKOM), and Knee injury and Osteoarthritis Outcome Score (KOOS) scores among Kellgren-Lawrence classifications

From: The influence of adipose-derived stromal vascular fraction cells on the treatment of knee osteoarthritis

 

Clinical score

Kellgren-Lawrence classification

P value

Grade II (11 patients)

Grade III (36 patients)

Grade IV (10 patients)

GradeII vs III

GradeII vs IV

GradeIII vs IV

Preoperative

WOMAC

27.7 ± 15.1

35.1 ± 17.5

37.6 ± 21.5

0.27

0.21

0.70

score

VAS

35.5 ± 18.6

52.1 ± 22.7

55.4 ± 30.8

0.07

0.06

0.70

 

JKOM

27.4 ± 15.3

37.4 ± 18.5

37.1 ± 20.8

0.15

0.24

0.97

 

KOOS

52.9 ± 12.0

48.6 ± 17.5

45.4 ± 14.6

0.46

0.28

0.56

12 months

WOMAC

11.2 ± 9.4

26.0 ± 16.6

25.7 ± 17.1

0.01a

0.04a

0.96

score

VAS

20.7 ± 20.2

37.4 ± 24.6

42.4 ± 25.8

0.07

0.045a

0.56

 

JKOM

14.4 ± 9.6

31.6 ± 20.1

32.2 ± 18.5

0.01a

0.03a

0.92

 

KOOS

68.5 ± 14.3

56.3 ± 17.9

56.1 ± 14.0

0.048a

0.08

0.97

Improvement

WOMAC

58.5 ± 26.5

22.8 ± 46.8

28.8 ± 22.1

0.02a

0.09

0.67

rate

VAS

14.8 ± 20.0

14.7 ± 20.9

13.0 ± 18.3

0.99

0.84

0.81

 

JKOM

34.4 ± 49.9

7.4 ± 56.6

5.7 ± 27.8

0.15

0.20

0.92

 

KOOS

19.1 ± 24.2

11.2 ± 27.9

17.7 ± 21.2

0.41

0.90

0.47

  1. Mean value ± Standard deviation (S.D.) a Statistically significant