Table 2 Comparisons of general information, clinical efficacy of the three groups
From: Antibiotic treatment regimens for bone infection after debridement: a study of 902 cases
Events | IV group | Oral group | Rifampicin group | P Value |
|---|---|---|---|---|
Number | 727 | 89 | 86 | – |
Sex ratio (male/female) | 3.9 (578/149) | 4.6 (73/16) | 3.3 (66/20) | 0.688 |
Average age(years) | 37.11 ± 1.62 | 40.30 ± 3.22 | 38.91 ± 2.54 | 0.130 |
Average duration of infection(months) | 70.3 ± 6.5 | 68.1 ± 11.8 | 75.9 ± 8.1 | 0.255 |
Type of infection (posttraumatic/hematologic) | (541/186) | (67/22) | (58/28) | 0.360 |
Recurrence rate of infection | 17.9%(130/727) | 10.1%(9/89) | 10.5%(9/86) | 0.051 |
Recurrence time(days) | 62.37 ± 6.93 | 58.56 ± 13.44 | 76.33 ± 17.48 | 0.851 |
Abnormal rate of ALT | 15.1%(110/727) | 18.0%(16/89) | 27.9%(24/86) | 0.026 |
Abnormal rate of AST | 16.4%(119/727) | 14.6%(13/89) | 13.9%(12/86) | 0.798 |
Abnormal rate of Cr | 1.1%(8/727) | 1.1%(1/89) | 2.3%(2/86) | 0.620 |
Positive rates of proteinuria | 3.2%(23/727) | 4.5%(4/89) | 9.3%(8/86) | 0.020 |