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Table 6 Results From 3 Studies Investigating Other Gut-Related Markers

From: Determining the association between fibromyalgia, the gut microbiome and its biomarkers: A systematic review

Author (Year)

Cohort

Material / Biomarker

Results

p-value for diff

FMS

Controls

Pimentel (2004) [17]

42 FMSa

111 IBS

15 HC

Breath(SIBO)

100%

IBS 84%

HC 20%

< 0.05

< 0.0001

Michalsen (2005) [18]

21 FMS9 RA

StoolpH & sIgAfollowing fasting

 

No differences between FMS vs RA groups or with different interventions

n.s.

14 FMS7 RA

StoolpH & sIgAfollowing MedDiet

  

n.s.

Goebel (2008) [19]

40 FMS

17 CRPS

57 HC

UrineGD permeabilitySI permeability

32.5%37.5%

CRPS 35.3%, HC 5%CRPS 17.6%, HC 0%

< 0.0001b < 0.0002&

  1. Key: a = 22 (54%) had IBS; b = p-value compared to controls; FMS Fibromyalgia; CRPS chronic regional pain syndrome; HC healthy controls; GD gastroduodenal; SI small intestine; IBS irritable bowel syndrome; RA rheumatoid arthritis; MedDiet Mediterranean Diet; SIBO small intestinal bacterial overgrowth; n.s. not significant.