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Table 3 Results from 5 Studies Investigating H. pylori

From: Determining the association between fibromyalgia, the gut microbiome and its biomarkers: A systematic review

Author (Year) Cohort Material H. pylori marker H. pylori positive (%)
FMS Controls p- value
Goebel (2008) [19] 33 FMS
17 CRPS
57 HC
Serum antibodies
IgA or IgG
33.0 HC: NT CRPS: 47.0 n.s.
Akkaya (2011) [20] 65 FMS
41 HC
Serum antibodies
IgA
IgG
30.8
67.7
17.1
43.9
0.169
0.025
Olama (2013) [21] 100 FMS
100 HC
Serum antibodies
IgA
IgG
50.0
68.0
24.0
32.0
<  0.001
< 0.001
Rodrigo (2013) [22] 104 FMS
125 IBS
Gastroduodenal biopsyH&E + Giemsa staining, polyclonal anti-H. pylori antibody, microbial cultures 42.0 46.0 n.s.
Gezici (2014) [23] 41# FMS Gastric biopsy
Culture
78.0
  1. Key: # all had dyspepsia; FMS fibromyalgia; HC healthy controls; CRPS chronic regional pain syndrome; IBS irritable bowel syndrome; NT not tested; NA not reported; n.s. not statistically significant.