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Fig. 5 | BMC Musculoskeletal Disorders

Fig. 5

From: Enhancement of tendon-bone interface healing and graft maturation with cylindrical titanium-web (TW) in a miniature swine anterior cruciate ligament reconstruction model: histological and collagen-based analysis

Fig. 5

Histological examinations in control limbs (a-c) and TW (titanium-web) limbs (d-h) 4 weeks after surgery. a Overview picture of the control limb (H.E. staining, 0.63x). The interface tissue was observed between the tendon and the anterior side bone. b Low-magnification (4x) view of the boxed area in the column of (a). c High-magnification (10x) view of the boxed area in the column of (b). Fibrous tissue and inflammatory cells were confirmed in the interface between the tendon and bone. d Overview picture of the TW limb (H.E. staining, 0.63x). Tendon and bone ingrowth were observed in anterior proximal part of the TW. e Low magnification (2x) view of the boxed area in the column of (d). f. g High-magnification (10x) view of the boxed area in the column of (e). Ingrowth of fibrous tissue and bone tissue in the TW was observed. h Villanueva’s Goldner staining. Calcified bone formation was confirmed in TW (10x). B: bone. I: interface tissue. PT: patellar tendon. TW: titanium-web. Bar scale 200 μm

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