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Fig. 6 | BMC Musculoskeletal Disorders

Fig. 6

From: Pigmented villous nodular synovitis mimicking metastases on 18F-FDG PET/CT in a patient with rectal mucosal melanoma: a case report

Fig. 6

Pathological appearances of the mass from the left ankle. a Low-power view of the hypocellular, ovoid shaped tumor. b Focal areas had increased cellular infiltrates consisting of lymphocytes, macrophages, and multinucleated giant cells, surrounded by highly collagenized stroma. Special staining with Melan-A (c) and HMB45 (d), both of which are markers of melanoma, yielded negative results. The pathologically proved diagnosis was pigmented villous nodular synovitis (PVNS)

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