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Table 1 Characteristics of surgical cases from which bone samples were collected

From: Non-invasive skin autofluorescence, blood and urine assays of the advanced glycation end product (AGE) pentosidine as an indirect indicator of AGE content in human bone

Characteristics

Cases

N = 100

Male

Female

p

Age (years)

58.5 ± 17.2

58.2 ± 17.4

58.9 ± 17.1

0.852

Gender, n (%)

 Male

54 (54%)

   

 Female

46 (46%)

   

Height (cm)

159.7 ± 9.2

164.9 ± 7.7

153.6 ± 6.9

< 0.001

Body weight (kg)

60.7 ± 11.4

65.7 ± 10.0

54.9 ± 10.1

< 0.001

BMI (kg/m2)

23.7 ± 3.4

24.1 ± 2.9

23.2 ± 3.9

0.210

eGFR (mL/min/1.73 m2)

83.4 ± 26.1

83.5 ± 23.4

83.2 ± 29.3

0.952

Serum pentosidine concentration (μg/mL)

0.05 ± 0.02

0.05 ± 0.02

0.05 ± 0.02

0.176

Urinary pentosidine concentration (pmol/mg Cr)

79.8 ± 40.8

71.7 ± 39.3

90.8 ± 40.8

0.056

Bone pentosidine (mmol/mol of collagen)

4.5 ± 2.5

4.8 ± 2.5

4.1 ± 2.4

0.202

Skin pentosidine (mmol/mol of collagen)

7.5 ± 3.5

6.9 ± 3.1

8.4 ± 3.8

0.051

Skin AGE reader (AU)

2.4 ± 0.5

2.4 ± 0.5

2.5 ± 0.5

0.488

  1. Data are the mean ± standard deviation, unless otherwise indicated
  2. AGE Advanced glycation end products, BMI Body mass index, Cr Creatinine, eGFR Estimated glomerular filtration rate
  3. p-value: male versus females